What is COVID-19

Origin

In the beginning of January 2020 a new coronavirus has been identified as a infectious agent causing a pneumonia outbreak in Wuhan, China where first symptoms were identified in December 2019.

COVID-19 is a contagious disease, caused by new coronavirus strain 2019-nCoV, which hasn’t been earlier indentified for humans. The disease is mainly transmitted by a droplet route, through coughing and sneezing which are common for infected people. At first the disease could show no symptoms, but eventually could include fever, cough, hard breathing, muscle pain and fatigue. In the later stages pneumonia and acute respiratory distresss syndrome can occur.

IgM & IgG antibodies are produced 3-7 days after being infected with a 2019-nCoV, thanks to that, they can be used as a diagnostic marker for early detection of the disease. Therefore detecting an IgM & IgG antibodies aimed at 2019-nCoV virus can be used as an additional screening method for early stages of Covid-19.

Coronaviruses are enveloped viruses which are widely spread amongst people, other mammals and birds, they can cause respiratory, intestine, liver and neurologic diseases.

Description

Coronavirus spreads through droplet route or close contact with a infected person or an animal, causing respiratory system infections. Incubation time can take up to 14 days but first symptoms usually occur after 5 to 6 days. First infection signs are similiar to influenza. People who lately has been travelling to higher risk countries or had a contact with a person which could be infected should monitor their health.

You should contact your doctor immediately if you have one of those symptoms:

  • high fever (more than 38°C ),
  • severe cough,
  • breathing problems.

To minimize risk of infection you should:

  • avoid contact with people showing symptoms of respiratory system disease,
  • wash your hands with soap more often,
  • avoid touching eyes, nose or mouth with a dirty hands,
  • avoid using the same utensils, dishes etc.
At the moment, there aren’t any cure or vaccine which would prevent being infected with this coronavirus. Rapid test for detecting IgG & IgM antibodies can be performed using whole blood, plasma or serum samples. No special equipment is needed for these tests. Package contains test strips and reagent. After adding the sample, it reacts with 2019-nCoV antigen infused particles on the test strip. Next, the mixture migrates up on the chromatographic membrane and reacts with anti-human IgG in the IgG test line if the sample contains 2019-nCoV IgG antibodies. Because of that a colored line will appear in the IgG testing area. Anti-human IgM is tested based on the same principle. If the sample doesn’t contain 2019-nCoV antibodies, none of the colored lines will appear in the testing area, which gives us a negative result. Test results can be read in just a couple minutes. These test are characterized by a good sensitivity and specifity.